Endocrine Abstracts

Background: It has been proposed that in the acute, untreated phase of thyrotoxicosis analysis of the peripheral eosinophil to monocyte ratio is a useful parameter to help differentiate thyroiditis from other forms of thyrotoxicosis without the need for radioiodine uptake scanning. (1).Methodology: We performed a retrospective search of our thyroid database for patients who had had a full blood count and radioiodine uptake scan prior to the commencement of antithyroid medi...

Aim: To determine whether metformin has beneficial effects on hirsutism in patientswithout diabetes mellitus.Methods: This was a randomised placebo controlled double blind parallel study of six months Metformin (1500milligrams per day)/placebo. The primary outcomes were change in hair growth rate on hirsutography and by Ferriman-Galwey score. Secondary endpoints were changes in biochemical parameters related to androgens and ins...

We report the case of a 32 year old female, with a family history of thyrotoxicosis, who presented with palpitations, weight loss, anxiety and diarrhoea. The patient was clinically thyrotoxic with tachycardia and tremor. On examination there was no goitre or evidence of Grave’s opthalmopathy. Biochemistry confirmed thyrotoxicosis with a T4 of 35 (11–23 pmol/l) and a T3 of 13.3 (3.5–6.5 pmol/l). Urea, electrolytes and liver function tests were normal. Electrocard...

Background: The most efficacious and acceptable form of testosterone replacement therapy remains a matter of debate. Proponents of testosterone implant therapy suggest implant therapy is the most acceptable form to patients with high continuation rates. Current practise within our hospital has led to increasing numbers of patients receiving implant therapy.Methods: We performed a retrospective postal questionnaire to determine the views of our implant recipients. Recipient...

BACKGROUNDAngina and Myocardial infarction have been reported in hyperthyroidism. Intense coronary artery spasm can be life threatening as it can lead to ventricular fibrillation and haemodynamic instability as reported in this patient.CASE HISTORYA 45-year-old lady was admitted with a history of head aches, palpitations, diarrhoea and weight loss. She was subsequently found to have thyrotoxicosis with the th...